How is PRF different from PRP?

PRP, or platelet-rich plasma, separates platelets from the blood in a liquid form that releases growth factors quickly after an injection. PRF, or platelet-rich fibrin, includes a higher concentration of fibrin, which forms a natural scaffold that releases growth factors at a slower pace. This extended release supports longer-lasting regenerative activity and steadier tissue repair. Many clients choosing PRF in Chicago prefer this sustained response because it works in closer alignment with the body’s natural healing process, rather than offering immediate synthetic changes.

Who is a good candidate for PRF?

PRF suits individuals seeking natural regeneration, improved texture, or support for fragile skin or thinning hair. It’s especially beneficial for those who prefer biologically aligned treatments that work with the body’s natural repair processes.

When will I see results?

Results vary from client to client. However, early improvements, such as increased hydration or softness, may appear within a few weeks. Over the following months, collagen production, elasticity, and overall skin or scalp quality improve as regeneration progresses. Clients seeking PRF or PDGF in Chicago often notice the most meaningful changes after completing their full recommended treatment series.

How many sessions will I need?

Most clients complete a series of 2-3 treatments spaced 4 to 6 weeks apart. Your provider designs a plan based on your skin condition, scalp health, and desired outcomes, allowing regenerative changes to build gradually and evenly.

Downtime varies from client to client but is minimal. Any mild swelling, tenderness, or redness that occurs usually resolves within a few days. Most clients return to their daily activities quickly after experiencing PRF or PDGF in Chicago while following aftercare guidance.

How long do results last?

Results can vary, but it’s possible to experience lasting benefits for up to a year. A structured series followed by periodic maintenance helps reinforce repair and extend improvements. Many people maintain their results from PRF or PDGF with annual or semi-annual sessions, depending on their goals.

Can PRF or PDGF pair with other treatments?

Yes. PRF and PDGF pair well with microneedling , neuromodulators , and dermal fillers when spaced appropriately. These combinations allow providers to address skin quality and structural concerns while maintaining natural-looking results.

PRF AND PDGF in Chicago

Natural Regeneration with Growth Factors

Build My Treatment Plan

Treatment Length:

60 to 90 minutes

Number of Sessions:

Series of 3

Results Duration:

Varies, 3 to 12 months

Autologous Renewal & Targeted Growth Factors

Refining how your body repairs itself.

Platelet & PDGF Concentration

Platelets or recombinant
Growth-factor rich

Fibrin Matrix

Slow-release support
Extended activity

Undereye Support

Improves thin skin
Softens crepiness

Facial Texture

Enhances smoothness
Refines tone

What It Treats

Skin Concerns

Fine lines
Wrinkles
Skin laxity
Dark circles
Hair loss/thinning
Skin rejuvenation
Dullness

Skin Benefits

Resilience
Hydration
Elasticity
Repair

PRF & PDGF Options

PRF Facial

A PRF Facial uses your body’s own growth factors to support collagen production, improve texture, and encourage gradual skin renewal with a natural, regenerative approach.

EZ Gel PRF

EZ Gel is created from your own blood to provide natural volume, hydration, and regenerative support, helping soften lines and improve skin quality without synthetic fillers.

PDGF Therapy

PDGF Therapy uses concentrated growth factors to support cellular repair, improve skin texture, and encourage gradual regeneration for healthier, more resilient skin over time.

Eye Restoration

Eye Restoration uses PRF or PDGF to support delicate under-eye skin, improving texture, hydration, and firmness while reducing the appearance of hollowness and fatigue.

Hair Restoration

Hair Restoration uses PRF or PDGF to support scalp health, stimulate dormant follicles, and encourage thicker, healthier hair growth through natural regenerative processes.

Compare Services

	Pure PDGF+	PRP/PRF	Exosomes
Blood Draw Required	No	Yes	No
Growth Factor Yield	Consistent & Potent	Highly Variable	Inconsistent, source-dependent
Safety & Sterility	Pharmaceutical-Grade	Potential Contamination	Usually Not Sterile, Possible Disease Risk
Ease of Use	Quick & Simple	Time & Labor-Intensive	Source Variability
FDA Approvals* (Related Applications)	4	N/A	None
Patient Experience	Predictable & Effortless	Draw Blood, Wait, Process	Uncertain Efficacy

Pure PDGF+

PRP/PRF

Exosomes

Blood Draw Required

Yes

Growth Factor Yield

Consistent & Potent

Highly Variable

Inconsistent, source-dependent

Safety & Sterility

Pharmaceutical-Grade

Potential Contamination

Usually Not Sterile, Possible Disease Risk

Ease of Use

Quick & Simple

Time & Labor-Intensive

Source Variability

FDA Approvals* (Related Applications)

N/A

None

Patient Experience

Predictable & Effortless

Draw Blood, Wait, Process

Uncertain Efficacy

What Is PRF & PDGF?

PDGF is a recombinant protein that powerfully activates fibroblasts, promotes new blood vessel formation, collagen/elastin production, and tissue repair. It provides consistent, high-potency results without the variability of autologous treatments

PRF, or platelet-rich fibrin, is a regenerative treatment made from your own blood. It concentrates platelets, fibrin, and platelet-derived growth factors (PDGF) that support cellular repair, collagen production, and tissue regeneration. PRF releases these growth factors gradually, helping to improve skin elasticity, texture, and overall resilience.

Why Choose PDGF or PRF?

Both PRF and Pure PDGF+ excel in their own powerful way. PRF is completely autologous using your own platelets and natural growth factors in a fibrin matrix for gradual, biologically harmonious regeneration that feels deeply natural. Pure PDGF+ (ariessence®) delivers a highly concentrated, pharmaceutical-grade recombinant Platelet-Derived Growth Factor for immediate hydration and precise, potent collagen stimulation with exceptional consistency and no blood draw required.

Both options support gradual collagen production, improved skin elasticity, under-eye rejuvenation, hair restoration, and healthier tissue over time. PDGF or PRF is ideal for those seeking subtle, biologically aligned improvements for the skin, undereye area, or scalp, with results that feel balanced.

Your Bespoke Wellness Path

Craft a treatment plan shaped around your rhythms, your goals, and the way you want to move through the world.

Build My Treatment Plan

Your PRF/PDGF Journey

Skin or Scalp Analysis

Your provider evaluates your skin quality or scalp health to determine where PRF or PDGF can deliver the most effective regenerative support.

Blood Draw (PRF)

We collect a small blood sample and prepare the PRF by spinning it in a centrifuge. Filled with platelets, fibrin, and growth factors, it aids in repairing your body.

Centrifugation

We process the sample using specialized centrifugation to isolate the PRF and create a regenerative solution designed to support optimal repair and renewal.

Targeted Placement

Your provider places PRF or PDGF into the targeted areas, allowing growth factors to absorb gradually and support collagen renewal, tissue repair, or healthier hair growth.